This fourth-quarter issue of Biomaterials Forum highlights both the scientific progress and community priorities shaping the biomaterials field as 2025 concludes. The issue features a tribute to Professor Ioannis Yannas, honoring his pioneering contributions to regenerative medicine and the development of artificial skin, alongside in-depth articles on advancing women’s health through sex-aware biomedical design, micro- and nanoscale titanium surface modifications to enhance implant biocompatibility, and the integration of 3D imaging, CAD, and orthopaedic biomaterials in patient-specific mandibular reconstruction. Complementing these features are updates on Society for Biomaterials initiatives, student perspectives on emerging research directions, AIMBE policy and leadership developments, and industry trends pointing to sustained growth across key biomaterials sectors—collectively underscoring the field’s impact, innovation, and commitment to translational and inclusive science.