2007 Technology & Training Forums
These Forums will be technically-based educational opportunities hosted by SFB corporate supporters.
- IonBond, LLC: “Coatings for Medical Device Applications”
- Lakeshore Biomaterials: “Tailoring of Poly(lactide-co-glycolide) to Control their Properties”
- Polymer Technology Group: “New Technology for Polymer Surface Modification: Self AssemblingMonolayer End Groups (SAME™)”
IonBond, LLC:
“Coatings for Medical Device Applications”
Wednesday April 18, 2007; 3:00 p.m. – 4:30 p.m.
Sheraton Ballroom I
Description:
Surface enhancement technologies are a viable, cost effective solution for the improvement of the physical properties of biomedical materials. This forum will summarize the capabilities, products and services of the IonBond, LLC Medthin Medical Group. It is intended to stimulate thought and discussion about potential applications for commercialization.
Physical Vapor Deposition (PVD), Chemical Vapor Deposition (CVD) and Plasma Assisted Chemical Vapor Deposition (PACVD) describe a group of surface enhancement technologies used to deposit wear and abrasion resistant thin film coatings with excellent adhesion. Medical and dental applications include orthopedic implants, cardiovascular implants, dental implants, catheters, surgical and dental instruments.
Various PVD deposition technologies are discussed together with product features and applications for medical grade coatings. More recent additions to the Medthin portfolio are a variety of diamond-like carbon (DLC) based coatings, a solid lubricant film and a 'patented' nano-textured biologic growth surface (TST).
Agenda:
- Advantages of IonBond® Coatings as Biomaterials
- PVD and PACVD Coating Deposition Technologies
- Implant and Surgical Instrument Applications
- New Coating Developments
- Medical Business Unit Capabilities
Goals:
Surface enhancement technologies can provide biocompatibility, wear and abrasion resistance and reduced costs through improved performance for the Medical Device Industry. The goal of this corporate forum is to provide a foundation for all participants to learn about the technologies, products and applications possible through the use of coating surface enhancement technologies.
Coating deposition technologies and practical application examples that take advantage of the properties offered by thin film coatings are presented. In addition, newly developed carbon based films, solid lubricant films and biologic in-growth nano-structured surfaces are discussed.
Who Should Attend
Individuals involved in the development, design or improvements of medical devices are invited to attend to learn how this powerful technology can be utilized to improve the performance and properties of accepted biomaterials. Members of Research and Development teams and product development team design engineers and application specialists are invited to attend and afterwards discuss application-related items with our experienced team.
Lakeshore Biomaterials:
“Tailoring of Poly(lactide-co-glycolide) to Control their Properties”
Wednesday April 18, 2007; 1:00 p.m. – 3:30 p.m.
Sheraton Ballroom I
Description:
The focus will be on the effects of composition, molecular weight, initiator types and polymer microstructure on the physical and mechanical properties of poly(lactide-co-glycolide) bioresorbable polymers including degradation. An overview of processing, sterilization and storage of bioresorbable polymers will be covered. We will summarize the applications of these polymers as matrices for drug delivery systems and as medical devices. If time allows, we will briefly touch on the bioresorbable polymers other than poly(lactide-co-glycolide) systems.
Agenda:
- Introduction and Overview of Poly(lactide-co-glycolide)
- Idealized Bioresorbable Biomaterial
- A Brief History of Poly(lactide-co-glycolide)
- Polymer Customization
- Effects of Composition
- Effects of Molecular Weight
- Effects of Initiator
- Effects of Microstructure
- Processing, Sterilization and Storage of Bioresorbable Polymers
- Applications
- Matrices for Drug Delivery Systems
- Medical Devices including Stents
- Tissue Engineering
- A Brief Summary of Other Bioresorbable Polymers (if time allows)
- Summary and Conclusion
- Questions
Goals:
This subject will be approached from a polymer science perspective explaining fundamental concepts such as molecular weight, glass transition temperature and microstructure. The goal is to educate scientists to enable them to make better informed decisions when selecting or designing a bioresorbable polymer for their application.
Who Should Attend?
The ideal attendees are students, scientists and engineers who have not been trained as polymer scientists, but are developing drug delivery systems or devices based on bioresorbable polymers. This course will provide a basic understanding of important concepts relating to polymer science and how they apply to bioresorbable polymers.
Polymer Technology Group:
“New Technology for Polymer Surface Modification: Self Assembling Monolayer End Groups (SAME™)”
Wednesday April 18, 2007; 3:00 p.m. – 4:30 p.m.
Sheraton Ballroom II
Description:
Self-assembling monomers (SAMs) are useful in research because they form well-defined monolayers for optional attachment of biologically-active molecules. However, their use in applications is limited by their fragility due, in part, to their monomolecular dimensions. Polymers with “Self-Assembling Monolayer End Groups’ (SAME) are designed to spontaneously form robust surfaces analogous to self-assembling monomers. Components can be manufactured by useful processing methods; e.g., molding, extrusion and spraying. Bulk properties are determined by the selection of polymer mid-block, while surface properties are dominated by the SAME moieties. This versatile architecture offers the potential for a seamless transition from R & D results with SAMs, to manufacturing new polymeric devices optimized for biomedical applications.
Agenda:
- Parallel optimization of devices and materials
- Nature of polymer surfaces: recent findings
- A versatile polymer structure for separately tailoring bulk and surface properties
- Similarities between SAMs and SAME polymer
- Enhancing existing biomaterials with SAME technology
- Surface modification
- Molecular weight control
- Improved processing
- Future potential in biomaterials development and applications
- Control of surface chemistry and nanostructure
- Surface characterization for applications
- Sum Frequency Vibrational Spectroscopy
Goals:
To review progress in the science and technology of high-performance biomaterials, and to instruct device developers in the optimization of materials for new/demanding applications.
Who Should Attend?
Physicians, scientists, engineers and technicians involved in the design or manufacturing of medical devices who desire to learn more about state-of-the-art materials and their optimization.