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These Forums will be technically-based educational opportunities
hosted by SFB corporate supporters.
FMC BioPolymer/NovaMatrix:
“Alginate Technology Workshop”
Description:
The Alginate Technology Workshop will begin with a “lecture-style”
overview of alginate structure and function and how this biopolymer
can be formulated for use in cell encapsulation and tissue
engineering applications. Three technology platforms will
be presented: Immobilization of cells in alginate gel beads,
self-gelling alginate systems, and alginate foams. The Workshop
will then offer attendees “hands-on” experience
with the different alginate technologies. Furthermore, practical
demonstrations relating to strength and degradability will
show the flexibility inherent in using alginate in such applications.
The Workshop will also review current Guidelines and Standards
for alginate used in Tissue Engineered Medical Products. A
new alginate product will be launched: RGD-alginate.
Agenda:
- Alginate structure and function
- Encapsulation in alginate gel beads
- Self-gelling alginate systems
- Alginate foam
- New Products
- Hands-on session
Goals:
The Workshop is intended to give attendees an overview of
several alginate-based technologies for tissue culture, cell
therapy and tissue engineering applications. Attendees will
gain an understanding of alginate structure and function and
how such knowledge can be put to use in developing biomaterial
applications. A review of current regulatory information regarding
alginate will be useful to those considering commercialization
of alginate-based products. The “hands-on” session
will give participants an opportunity to make and handle different
alginate formulations specifically designed for cell immobilization
and tissue engineering applications.
Who Should Attend?
The prospective attendee would be a researcher with experience
in biomaterial, scaffold and/or matrix formulations. Those
interested in cell therapy (cell encapsulation) and tissue
engineering scaffolds will also benefit by attending this
Workshop.
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Invibio,
Inc.: “Using Novel High Performance Polyetheretherketone
Biomaterials for Implantable Medical Devices”
Description:
This forum will discuss the novel uses and performance profile
of Polyetheretherketone with carbon fibres added to make commercial
FDA cleared and CE marked medical devices. The forum will
present accepted theories and practices of fibre reinforcement
and address issues of functional performance and biocompatibility.
Participants are encouraged to bring real-world
applications for the workshop and discussion with our expert
panel.
Polyetheretherketone is an important biomaterial
which is selected in preference to metals in some common implantable
devices. While the base polymer has excellent mechanical properties
compared with other materials of its class, the addition of
reinforcing carbon.fibres can further increase its strength,
stiffness and wear resistance.
Agenda:
- Polyetheretherketone composite products
- Biocompatibility and tissue interactions of Polyetheretherketone
composites and carbon fibre compounds
- Polyetheretherketone composite materials and processing
- End-user prospective
- Workshop and case history discussion with panel of experts
Goals:
- To introduce to a new audience an important biomaterial;
- To describe the use of carbon fibres as a means of enhancing
the mechanical properties of the base polymer and give examples
of successful applications;
- To describe the theory and practice of fibre reinforcement
and production processing capabilities of this class of
materials;
- To describe the achievable mechanical properties in comparison
with traditional materials used for medical implants;
- To provide participants with the opportunity to discuss
real-life ideas and applications with leading experts in
device design.
Who Should Attend?
Surgeons, medical device engineers, students and academia.
Anyone interested in alternatives to traditional materials
that offer performance benefits and features not otherwise
available. Someone who designs medical devices, or specifies
materials, or is involved in the manufacture of medical devices.
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IonBond, LLC:
“Coatings for Medical Device Applications”
Description:
Surface enhancement technologies are a viable, cost effective
solution for the improvement of the physical properties of
biomedical materials. This forum will summarize the capabilities,
products and services of the IonBond, LLC Medthin Medical
Group. It is intended to stimulate thought and discussion
about potential applications for commercialization.
Physical Vapor Deposition (PVD), Chemical Vapor Deposition
(CVD) and Plasma Assisted Chemical Vapor Deposition (P A CVD)
describe a group of surface enhancement technologies used
to deposit wear and abrasion resistant thin film coatings
with excellent adhesion. Medical and dental applications include
orthopedic implants, cardiovascular implants, dental implants,
catheters, surgical and dental instruments.
Various PVD deposition technologies are discussed together
with product features and applications for medical grade coatings.
More recent additions to the Medthin portfolio are a variety
of diamond-like carbon (DLC) based coatings, a solid lubricant
film and a 'patented' nano-textured biologic growth surface
(TST).
Agenda:
- Advantages of IonBond® Coatings as Biomaterials
- PVD and P ACVD Coating Deposition Technologies
- Implant and Surgical Instrument Applications
- New Coating Developments
- Medical Business Unit Capabilities
Goals:
Surface enhancement technologies can provide biocompatibility,
wear and abrasion resistance and reduced costs through improved
performance for the Medical Device Industry. The goal of this
corporate forum is to provide a foundation for all participants
to learn about the technologies, products and applications
possible through the use of coating surface enhancement technologies.
Coating deposition technologies and practical application
examples that take advantage of the properties offered by
thin film coatings are presented. In addition, newly developed
carbon based films, solid lubricant films and biologic in-growth
nano-structured surfaces are discussed.
Who Should Attend?
Individuals involved in the development, design or improvements
of medical devices are invited to attend to learn how this
powerful technology can be utilized to improve the performance
and properties of accepted biomaterials. Members of Research
and Development teams and product development team design
engineers and application specialists are invited to attend
and afterwards discuss application-related items with our
experienced team.
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Medtronic,
Inc.: “Long Term Biostability of Polymeric Biomaterials”
Description:
Biostability is critical for biomaterials in general, but
it is much more critical for those biomaterials used for chronic
implantation. This is not only because these materials require
long term functional and mechanical integrity, but also because
biostability can affect chronic biocompatibility. For example,
chemical degradation may result in the loss of material properties
and functions, but could also lead to the release of toxic
degradation products into surrounding tissues. In this lecture,
we will first discuss some common chemical, physical, and
combined factors that can lead to degradation of polymeric
materials. Secondly, we will discuss in vitro and in vivo
chemical stability tests for material screening. Lastly, we
will discuss the selection of polymeric materials for long
term implantation.
Agenda:
- Biostability, biocompatibility, and their relationships
for chronic implant materials.
- Common causes for materials to degrade.
- In vitro and in vivo chemical stability test for polymers
- Material selection guidelines for chronic implant applications
Goals:
The goal of the tutorial is to help participants to learn
the basic principles of biostability of polymeric materials
and to understand the in vitro and in vivo material stability
tests.
Who Should Attend?
Students and industrial researchers who are interested in
biomaterials for chronic implant applications should attend
the tutorial. The principles and test methods presented in
the lecture should be beneficial to their research, development
and use of biomaterials.
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Polymer Technology
Group: “A New Approach for Tailoring Biomaterials Properties:
Polymers with Self Assembling End Groups”
Description:
Self-assembling monolayers (SAMs) are useful in research because
they create well defined surfaces for optional attachment
of biologically-active molecules, but their use in applications
is limited by their fragility. New thermoplastic biomaterials
are built from backbone segments and surface-modifying end
groups (SME). Recent work demonstrates similarities between
SME polymer surfaces and those created from analogous self
assembling thiol monomers on gold. The more robust polymer
systems can be fabricated by high-speed processing methods
and have the potential to serve in many applications: bulk
properties are determined by the polymer mid-block, while
surface properties are dominated by the SMEs. This versatile
architecture offers a seamless transition from R&D results
with SAMs to manufacturing of new polymers tailored for biomedical
applications.
Agenda:
- Parallel optimization of device and materials
- Nature of polymer surfaces
- A versatile polymer structure for separately tailoring
bulk and surface properties
- Similarities between SAMs and SME polymers
- Existing biomaterials with SMEs
- Future potential in biomaterials development and applications
- Control of surface nanostructure with amphipathic
SMEs
Goals:
To review progress in the science and technology of high-performance
biomaterials, and to instruct device developers in the optimization
of materials for new/demanding applications.
Who Should Attend?
Physicians, scientists, engineers and technicians involved
in the design or manufacturing of medical devices who desire
to learn more about state-of-the-art materials and their optimization.
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